WebAbstract. Objective: Curcumin being used to treat various chronic diseases while its poor bioavailability issue limited its wide clinical application as a therapeutic agent. The aim of this work was to prepare curcumin-loaded self-assembled micelles using soluplus and solutol ® HS15 (SSCMs) to enhance curcumin’s solubility and thus oral bioavailability. WebWhen curcumin is viewed under a 535–600 mm filter, it emits green fluorescence. Hence intracellular uptake of curcumin and curcumin-loaded self-assembled nanoparticles was determined using a fluorescence microscope (Olympus IX51, USA) attached to an Olympus camera (DP70 Digital, USA).
One-step self-assembly of curcumin-loaded zein/sophorolipid ...
WebOne-step self-assembly of curcumin-loaded zein/sophorolipid nanoparticles: physicochemical stability, redispersibility, solubility and bioaccessibility - Food & Function (RSC Publishing) Maintenance work is planned for Wednesday 5th April 2024 from 09:00 to 10:30 (BST). WebJan 8, 2024 · The strongly hydrophobic curcumin was embedded within the hydrophobic cores of zein nanoparticles using an antisolvent method, while the weakly hydrophobic EGCG was adsorbed to the region between... graig brown
Curcumin loaded self assembled lipid-biopolymer nanoparticles …
WebIn this study, curcumin has been encapsulated in an amphiphilic biopolymer to enhance its water solubility. This was accomplished through self-assembly of octenyl succinic anhydride–short glucan chains (OSA–SGC) and curcumin. The nanoparticles were prepared with the degree of substitution (DS) of 0.112, 0.286 and … WebAug 16, 2024 · Curcumin nanosystems improve the nature of curcumin as a therapeutic agent, overcoming such challenges while increasing bioavailability. Interestingly, the entrapment and nanodrug-loading efficacy are highly reliant on the manufacturing process and the carrier structure used to carry the nano drugs. WebAug 1, 2024 · Jiang et al. prepared stearic acid-g-chitosan oligosaccharide polymers that self-assembled to form polymer micelles via dialysis for loading hydrophobic substances (Jiang et al., 2024). The average size of the obtained micelles was 239.3 ± 3.1 nm, and the polydispersity index (PDI) was approximately 0.327. graig community centre bassaleg