Haemodynamics-driven developmental pruning

Author: agys

August undefined, 2024

WebOur findings demonstrate the existence of vessel pruning and its crucial role in the formation of the midbrain vasculature (Figure 8G). This vessel pruning leads to a developmental reduction... WebHere we report that the developing vasculature in the zebrafish midbrain undergoes not only angiogenesis but also extensive vessel pruning, which is driven by changes in blood flow. This pruning process shapes the initial exuberant interconnected meshwork into a …

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Haemodynamics-Driven Developmental Pruning of Brain Vasculature in … WebAug 14, 2012 · Vessel pruning occurred preferentially at loop-forming segments via a process mainly involving lateral migration of endothelial cells (ECs) from pruned to unpruned segments rather than EC apoptosis, leading to gradual reduction in the vasculature … folding stairs for crawl space

Haemodynamics-Driven Developmental Pruning of Brain …

WebMay 26, 2024 · In summary, we present a broad methodological overview ranging from image enhancement to segmentation with a mixed approach of experimental, simulated, and augmented datasets to assess and validate vascular segmentation using the zebrafish brain vasculature as an example. © 2024 The Authors. Current Protocols published by Wiley … WebDec 1, 2024 · Systemic hypertension and pulmonary arterial hypertension (PAH) are two distinct diseases developing in networks characterized by different physiology, different pressure conditions (high pressures in the systemic circuit and low pressures in the pulmonary circuit), and different vessel compliance. WebMay 12, 2024 · Haemodynamics-driven developmental pruning of brain vasculature in zebrafish. PLoS Biol. 2012; 10:e1001374. doi: 10.1371/journal.pbio.1001374 Google Scholar; 13. Bracko O, Cruz Hernández JC, Park L, Nishimura N, Schaffer CB. Causes and consequences of baseline cerebral blood flow reductions in Alzheimer’s disease. J Cereb … folding stairs for a seawall

Developmental facilitation of the midbrain blood flow. (A ...

Endothelial mechanosensing: A forgotten target to treat vascular ...

WebAug 14, 2012 · As expected, pruning increased mean blood flow velocity and decreased the number of vessels exhibiting bidirectional blood flow. It also turned out that vessel segments that were pruned later generally had lower blood flow velocity than neighboring unpruned … WebAug 14, 2012 · They revealed that the 'vessel pruning' that naturally takes place during development (whereby the vasculature develops its optimum, relatively simplified final form through the disappearance... egyptian goddess of war and huntingWebThis vessel pruning leads to a developmental reduction of vascular network complexity that may facilitate efficient routing of midbrain blood flow. We further revealed that changes of blood flow ... folding stairs attic

"WebThus, changes of blood flow drive vessel pruning via lateral migration of ECs, leading to the simplification of the vasculature and possibly efficient routing of blood flow in the developing brain. Citation: Chen Q, Jiang L, Li C, Hu D, Bu J-w, et al. (2012) Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish. PLoS Biol ... " - Haemodynamics-driven developmental pruning

Haemodynamics-driven developmental pruning

Pruning brain vasculature for efficiency. - Abstract - Europe PMC

Webtitle = "Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish", abstract = "The brain blood vasculature consists of a highly ramified vessel network that is tailored to meet its physiological functions. How the brain vasculature is formed has long been fascinating biologists.

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WebAug 14, 2012 · Haemodynamics-driven developmental pruning of brain vasculature in zebrafish. ... that the developing vasculature in the zebrafish midbrain undergoes not only angiogenesis but also extensive vessel pruning, which is driven by changes in blood flow. This pruning process shapes the initial exuberant interconnected meshwork into a … WebMy current research focuses on theoretical and computational neuroscience, network dynamics, wave turbulence, applied dynamical systems, and applied stochastic processes and includes the development of theoretical and computational tools for their …

WebAug 1, 2012 · Developing brain blood vasculature undergoes not only angiogenic sprouting (arrowheads), but also extensive vessel pruning (arrows) driven by blood flow. Figures - available via license: Creative ... WebJul 26, 2024 · Abstract Angiogenesis, arteriogenesis, and pruning are revascularization processes essential to our natural vascular development and adaptation, as well as central players in the onset and development of pathologies such …

WebAug 14, 2012 · Chen Q, Jiang L, Li C, Hu D, Bu J-w, et al. Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish. PLoS Biol , 10(8): e1001374 DOI: 10.1371/journal.pbio.1001374 Cite This Page : WebMy current research focuses on theoretical and computational neuroscience, network dynamics, wave turbulence, applied dynamical systems, and applied stochastic processes and includes the development of theoretical and computational tools for their applications in physics, biology, and neuroscience. Selected Publications

WebVessel pruning occurred preferentially at loop-forming segments via a process mainly involving lateral migration of endothelial cells (ECs) from pruned to unpruned segments rather than EC apoptosis, leading to gradual reduction in the vasculature complexity with …

Webpruning observed later on. Moreover, when blood flow through a particular vessel segment was blocked by injection of fluorescent micro-beads, pruning invari-ably eliminated that segment. Therefore, pruning likely serves to eliminate func-tionally redundant structures from the brain vasculature. If this is the case, it raises the question of egyptian goddess sethWebMy current research focuses on theoretical and computational neuroscience, network dynamics, wave turbulence, applied dynamical systems, and applied stochastic processes and includes the development of theoretical and computational tools for their … egyptian goddess perfume roll onWebMy current research focuses on theoretical and computational neuroscience, network dynamics, wave turbulence, applied dynamical systems, and applied stochastic processes and includes the development of theoretical and computational tools for their … folding stairs for saleWebHaemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish Article Full-text available Aug 2012 Qi Chen Luan Jiang Chun Li [...] Jiulin du The brain blood vasculature consists... folding stairs from wall plansWebVessel pruning occurred preferentially at loop-forming segments via a process mainly involving lateral migration of endothelial cells (ECs) from pruned to unpruned segments rather than EC apoptosis, leading to gradual reduction in the vasculature complexity with … egyptian goddess statueWebAug 14, 2012 · Finally, we show that pruning events can be predicted using a haemodynamics based mathematical model of the midbrain … folding stair dog carWebAug 13, 2024 · This shift provides ‘division of labor’ among the neural cells and tissues. It allows taking over of the specific barrier and neural support functions. Tight junctions are present in BBB which... egyptian goddess soap