WebJul 18, 2024 · 1 Half-life: 68 hours (~3 days): 50% ; 2 Half-lives: 136 hours (~6 days): 25% ; 3 Half-lives: 204 hours (~9 days): 12.5%; 4 Half-lives: … Azithromycin prevents bacteria from growing by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome, thus inhibiting translation of mRNA. Nucleic acid synthesis is not affected. Azithromycin is an acid-stable antibiotic, so it can be taken orally with no need of protection from gastric acids. It is readily absorbed, but absorption is greater on an empty stomach. Time to pea…
[Clinical pharmacokinetics of azithromycin] - PubMed
WebPlasma concentrations of azithromycin following single 500 mg oral and i.v. doses declined in a polyphasic pattern with a mean apparent plasma clearance of 630 mL/min and … WebIn these studies (500 mg Day 1, 250 mg Days 2-5), there was no significant difference in the disposition of azithromycin between male and female subjects. Plasma concentrations of azithromycin following single 500 mg oral and I.V. doses declined in a polyphasic pattern resulting in an average terminal half-life of 68 hours. gun rack weoght bench
azithromycin half life - MedHelp
WebJan 1, 2001 · Owing to azithromycin's prolonged half-life, shorter and shorter dosage regimens are being studied for treatment of respiratory tract infections. ... oral azithromycin, 500 mg (two 250 mg tablets) daily for 3 days; and (ii) oral azithromycin 1500 mg (six 250 mg tablets). All doses were administered with 240 mL of tap water after the subjects ... WebApr 4, 2024 · The adult azithromycin dose is 500-2000 mg in multiple or single doses. For most infections, azithromycin is taken once daily for a relatively short course of treatment (usually five days). The first dose is often a "double dose," twice as much as the remainder of the doses given. WebPlasma concentrations of azithromycin following single 500 mg oral and I.V. doses declined in a polyphasic pattern with a mean apparent plasma clearance of 630 mL/min and terminal elimination half-life of 68 hours. The prolonged terminal half-life is thought to be due to extensive uptake and subsequent release of drug from tissues. gun rack wayne\\u0027s world